Tenka is shackled and brought in to see Botan, Hirari and Ōta. It is revealed that Tenka was a test subject for a miracle drug developed from Orochi cells. After learning from Botan that Soramaru is the real Orochi's vessel and has been captured by Shirasu, Tenka breaks free from the shackles to search for his brothers. Meanwhile, Sōsei informs Kiiko that Iwakura underwent a major surgery with an Orochi serum which can double healing capabilities. In the woods, the Yamainu Squad confront and defeat the head warden Orita and the surrounding armed prisoners. After Botan arrives and tells the Yamainu Squad that the Orochi's vessel must be exposed to the sunlight, they deduce that using the Lake Biwa underground canal will help them succeed. Nishiki finds Soramaru, realizing that he is no longer the same, but she runs off with the twin swords. After Kagami attacks Kitamura and Tsuchiya, a tearful Chūtarō ends up escaping and finds Nishiki holding the twin swords. Chūtarō heads to the canal as Soramaru follows, while Botan and Nishiki handle Shirasu. The Yamainu Squad are up against Kotaro and the Fuma clansmen. As Soramaru and Chūtarō fight, Tenka breaks through the canal.