Hapless lab technician Nobuo Tanaka consumes some pills at his laboratory to cure a cold. Unknown to him, however, the pills are actually experimental drugs that enhance his flatulence to a lethal degree. As the toxic gas escaping him kills everyone in his vicinity, he is ordered by his superiors to retreat to the company headquarters in Tokyo. The journey to the city is made all the more arduous as Nobuo struggles with his deadly odor while the police, military, and foreign adversaries are hot on his trail.