At the scene of Makoto's death Jin burns the notebooks he had in his possession. He pays off a young boy who found the body to secure his silence, but kills the cleaner. A flashback to years earlier, shows Janome's experiments into immortality on unwilling prisoners using venom-based drugs. Yoshio, one of the inmates, kills himself with a piece of stolen glass, but his friend Iori uses the glass to kill 38 fellow prisoners and 14 guards and escape. He is captured by a Nue agent who refers to himself as "Kotodama" and is taken before the shogun as a prefect candidate because of his powerful thirst for life...